Article
Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.
PloS one - 2 Nov 2009
Folkersen Lasse, Kyriakou Theodosios, Goel Anuj, Peden John, Mälarstig Anders, Paulsson-Berne Gabrielle, Hamsten Anders, Hugh Watkins, Franco-Cereceda Anders, Gabrielsen Anders, Eriksson Per
Abstract excerpt
BACKGROUND: Several genome-wide association studies have recently linked a group of single nucleotide polymorphisms in the 9p21 region with cardiovascular disease. The molecular mechanisms of this link are not fully understood. We investigated five different expression microarray datasets in order to determine if the genotype had effect on expression of any gene transcript in aorta, mammary artery, carotid plaque...
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