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Article

Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression.

PLoS genetics - 8 Apr 2010

Cunnington Michael S, Santibanez Koref Mauro, Mayosi Bongani M, Burn John, Keavney Bernard

Abstract excerpt

Single nucleotide polymorphisms (SNPs) on chromosome 9p21 are associated with coronary artery disease, diabetes, and multiple cancers. Risk SNPs are mainly non-coding, suggesting that they influence expression and may act in cis. We examined the association between 56 SNPs in this region and peripheral blood expression of the three nearest genes CDKN2A, CDKN2B, and ANRIL using total and allelic expression in two...

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Identifiers

PMID: 20386740
DOI: 10.1371/journal.pgen.1000899
PMCID: PMC2851566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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