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Article

ANRIL expression is associated with atherosclerosis risk at chromosome 9p21.

Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2010

Holdt Lesca M, Beutner Frank, Scholz Markus, Gielen Stephan, Gäbel Gábor, Bergert Hendrik, Schuler Gerhard, Thiery Joachim, Teupser Daniel

Abstract excerpt

OBJECTIVE: We tested the hypothesis that expression of transcripts adjacent to the chromosome 9p21 (Chr9p21) locus of coronary artery disease was affected by the genotype at this locus and associated with atherosclerosis risk. METHODS AND RESULTS: We replicated the locus for coronary artery disease (P=0.007; OR=1.28) and other manifestations of atherosclerosis such as carotid plaque (P=0.003; OR=1.31) in the...

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PMID: 20056914
DOI: 10.1161/ATVBAHA.109.196832

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