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Article

Resequencing and clinical associations of the 9p21.3 region: a comprehensive investigation in the Framingham heart study.

Circulation - 19 Feb 2013

Johnson Andrew D, Hwang Shih-Jen, Voorman Arend, Morrison Alanna, Peloso Gina M, Hsu Yi-Hsiang, Thanassoulis George, Newton-Cheh Christopher, Rogers Ian S, Hoffmann Udo, Freedman Jane E, Fox Caroline S, Psaty Bruce M, Boerwinkle Eric, Cupples L Adrienne, O'Donnell Christopher J

Abstract excerpt

BACKGROUND: 9p21.3 is among the most strongly replicated regions for cardiovascular disease. There are few reports of sequencing the associated 9p21.3 interval. We set out to sequence the 9p21.3 region followed by a comprehensive study of genetic associations with clinical and subclinical cardiovascular disease and its risk factors, as well as with copy number variation and gene expression, in the Framingham...

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Calcinosis
Chromosomes, Human, Pair 9
Coronary Artery Disease
Cyclin-Dependent Kinase Inhibitor p15

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Cyclin-Dependent Kinase Inhibitor p16

Myocardial Infarction

RNA, Long Noncoding

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Identifiers

PMID: 23315372
DOI: 10.1161/CIRCULATIONAHA.112.111559
PMCID: PMC3686634

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