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Article

Functional genomics of the 9p21.3 locus for atherosclerosis: clarity or confusion?

Current cardiology reports - 1 Jul 2014

Chen Hsiao-Huei, Almontashiri Naif A M, Antoine Darlène, Stewart Alexandre F R

Abstract excerpt

The 9p21.3 locus was the first to yield to genome-wide association studies (GWAS) seeking common genetic variants predisposing to increased risk of coronary artery atherosclerotic disease (CAD). The 59 single nucleotide polymorphisms that show highest association with CAD are clustered in a region 100,000 to 150,000 base pairs 5' to the cyclin-dependent kinase inhibitors CDKN2B (coding for p15(ink4b)) and CDKN2A...

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PMID: 24893939
DOI: 10.1007/s11886-014-0502-7

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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