Article
[Genetic variants, cardiovascular risk and genome-wide association studies].
Revista espanola de cardiologia - 1 Jun 2011
Companioni Osmel, Rodríguez Esparragón Francisco, Fernández-Aceituno Alfonso Medina, Rodríguez Pérez José Carlos
Abstract excerpt
Genome-wide association studies have shown an association between single nucleotide polymorphisms (SNPs) and coronary artery disease and myocardial infarction in new chromosomal regions: 1p13.1, 2q36.3, 9p21 and 10q11.21. The SNPs from the 9p21 region constitute a risk haplotype due to the strong linkage disequilibrium in this area. These SNPs have been extensively replicated in several European and Asian...
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