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Article

Genetic analysis of the 9p21.3 CAD risk locus in Asian Indians.

Thrombosis and haemostasis - 5 May 2014

Shanker Jayashree, Arvind Prathima, Jambunathan Srikarthika, Nair Jiny, Kakkar Vijay

Abstract excerpt

The 9p21.3 locus is the best replicated region to date for coronary artery disease (CAD). We investigated the association of 9p21.3 common variants with CAD, candidate gene expression including ANRIL, a non-coding RNA, followed by in vitro validation. Five variants, rs10757278, rs10757274, rs2383206, rs1333049 and rs4977574 were genotyped in 1,034 cases and 1,034 controls. Gene expression of C9orf5, MTAP1, MTAP...

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Identifiers

PMID: 24452806
DOI: 10.1160/TH13-08-0706

Genes

CAD
MTAP

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