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Article

Evaluation of Macaca mulatta as a model for genotoxicity studies.

Mutation research - 19 Feb 2009

Dobrovolsky Vasily N, Shaddock Joseph G, Mittelstaedt Roberta A, Manjanatha Mugimane G, Miura Daishiro, Uchikawa Makoto, Mattison Donald R, Morris Suzanne M

Abstract excerpt

We have investigated the use of peripheral blood from the nonhuman primate (NHP) rhesus monkey (Macaca mulatta) as a model system for mutation detection. The rhesus monkey is metabolically closer to humans than most common laboratory animals, and therefore may be a relevant model for hazard identification and human risk assessment. To validate the model, conditions were determined for in vitro selection and...

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PMID: 19073277
DOI: 10.1016/j.mrgentox.2008.11.006

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GPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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