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Mouse Pig-a and micronucleus assays respond to N-ethyl-N-nitrosourea, benzo[a]pyrene, and ethyl carbamate, but not pyrene or methyl carbamate.

Environmental and molecular mutagenesis - 1 Jan 2016

Labash Carson, Avlasevich Svetlana L, Carlson Kristine, Berg Ariel, Torous Dorothea K, Bryce Steven M, Bemis Jeffrey C, MacGregor James T, Dertinger Stephen D

Abstract excerpt

This laboratory previously described a method for scoring the incidence of peripheral blood Pig-a mutant phenotype rat erythrocytes using immunomagnetic separation in conjunction with flow cytometric analysis (In Vivo MutaFlow®). The current work extends the method to mouse blood, using the frequency of CD24-negative reticulocytes (RET(CD24-)) and erythrocytes (RBC(CD24-)) as phenotypic reporters of Pig-a gene...

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PMID: 26186091
DOI: 10.1002/em.21965

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RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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