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Article

The in vivo Pig-a gene mutation assay, a potential tool for regulatory safety assessment.

Environmental and molecular mutagenesis - 1 Jan 2000

Dobrovolsky Vasily N, Miura Daishiro, Heflich Robert H, Dertinger Stephen D

Abstract excerpt

The Pig-a (phosphatidylinositol glycan, Class A) gene codes for a catalytic subunit of the N-acetylglucosamine transferase complex involved in an early step of glycosylphosphatidyl inositol (GPI) cell surface anchor synthesis. Pig-a is the only gene involved in GPI anchor synthesis that is on the X-chromosome, and research into the origins of an acquired genetic disease involving GPI anchor deficiency (paroxysmal...

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Source

Identifiers

PMID: 20857433
DOI: 10.1002/em.20627

Genes

GPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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