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Article

Endothelial nitric oxide synthase gene polymorphisms and the renal hemodynamic response to L-arginine.

Kidney international - 1 Feb 2009

Cherney David Z I, Scholey James W, Zhou Joyce, Zimpelmann Joseph, Kennedy Christopher, Burns Kevin D, Lai Vesta, Miller Judith A

Abstract excerpt

Nitric oxide is generated from L-arginine by nitric oxide synthase (NOS), an enzyme that exists in several isoforms. Some studies found that a polymorphism (G894T) in the endothelial NOS gene was associated with decreased nitric oxide bioactivity and vascular complications. However, it is not known whether the enzyme had a reduced activity. Here we measured the effect of an infusion of L-arginine on renal...

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Identifiers

PMID: 19037250
DOI: 10.1038/ki.2008.574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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