Article
Relationship between the G894T polymorphism (Glu298Asp variant) in endothelial nitric oxide synthase and nitric oxide-mediated endothelial function in human atherosclerosis.
American journal of medical genetics - 22 Apr 2001
Guzik T J, Black E, West N E, McDonald D, Ratnatunga C, Pillai R, Channon K M
Abstract excerpt
Nitric oxide (NO), produced by endothelial nitric oxide synthase (eNOS), plays important roles in normal vascular homeostasis, and reduced endothelial NO bioactivity is an important feature of vascular disease states. The Glu298Asp (G894T) polymorphic variant of eNOS has been associated with vasc...
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