Article
Endothelial nitric oxide synthase polymorphisms and hypertension.
Current hypertension reports - 1 Feb 2003
Hingorani Aroon D
Abstract excerpt
The human endothelial nitric oxide synthase (eNOS) gene is highly polymorphic. Evidence for the involvement of eNOS single nucleotide polymorphisms in the development of essential hypertension is limited, though the eNOS Glu298Asp polymorphism appears to influence the blood pressure response to exercise. This variant also influences endothelial function, with its effects becoming manifest during the adaptive...
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