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Article

Interactive effects of the ACE DD polymorphism with the NOS III homozygous G849T (Glu298-->Asp) variant in determining endothelial function in coronary artery disease.

Vascular medicine (London, England) - 1 Jan 2003

Schmidt Michael A, Chakrabarti Anjan K, Kehrer Chris, Pfeninnger Dana, Brook Robert D, Kaciroti Niko, Duvernoy Claire, Killeen Anthony A, Rajagopalan Sanjay

Abstract excerpt

The products of nitric oxide synthase (NOS) and angiotensin-converting enzyme (ACE) play a critical role in determining vessel wall structure and function. Polymorphisms in both genes have been independently demonstrated to influence propensity to cardiovascular events. The purpose of this study was to determine the influence of the homozygous G849T (Glu298-->Asp) polymorphism in NOS III on peripheral conduit...

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Source

Identifiers

PMID: 14989558
DOI: 10.1191/1358863x03vm486oa

Genes

ACE

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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