Article
Pharmacogenetic influence of eNOS gene variant on endothelial and glucose metabolism responses to L-arginine supplementation: Post hoc analysis of the L-arginine trial.
Metabolism: clinical and experimental - 1 Nov 2015
Monti Lucilla D, Galluccio Elena, Fontana Barbara, Spadoni Serena, Comola Mauro, Marrocco Trischitta Massimiliano M, Chiesa Roberto, Comi Giancarlo, Bosi Emanuele, Piatti Piermarco
Abstract excerpt
OBJECTIVE: To evaluate whether variants of the eNOS gene are associated with endothelial and metabolic responses to L-arginine (L-arg) supplementation. MATERIAL AND METHODS: We examined a single nucleotide polymorphism of the eNOS gene (rs753482-A>C) to investigate the effects of this variant on endothelial function (EF), colony-forming unit-endothelial cell (CFU-EC) number, asymmetric-dimethylarginine (ADMA)...
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