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Article

Interaction with RPA is necessary for Rad52 repair center formation and for its mediator activity.

The Journal of biological chemistry - 24 Oct 2008

Plate Iben, Hallwyl Swee C L, Shi Idina, Krejci Lumir, Müller Christian, Albertsen Line, Sung Patrick, Mortensen Uffe H

Abstract excerpt

Homologous recombination (HR) is a major DNA repair pathway and therefore essential for maintaining the integrity of the genome. HR is catalyzed by proteins encoded by genes of the RAD52 epistasis group, including the recombinase Rad51 and its mediator Rad52. HR proteins fused with green fluorescent protein form foci at damaged DNA reflecting the assembly of repair centers that harbor a high concentration of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epistasis, Genetic

Share to Microscopy, Fluorescence

Share to Rad51 Recombinase

Share to Rad52 DNA Repair and Recombination Protein

Share to Recombination, Genetic

Share to Two-Hybrid System Techniques

Source

Open in PubMed Open full text

Identifiers

PMID: 18703507
DOI: 10.1074/jbc.M804881200
PMCID: PMC2570898

Genes

RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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