Article
Control of Rad52 recombination activity by double-strand break-induced SUMO modification.
Nature cell biology - 1 Nov 2006
Sacher Meik, Pfander Boris, Hoege Carsten, Jentsch Stefan
Abstract excerpt
Homologous recombination is essential for genetic exchange, meiosis and error-free repair of double-strand breaks. Central to this process is Rad52, a conserved homo-oligomeric ring-shaped protein, which mediates the exchange of the early recombination factor RPA by Rad51 and promotes strand anne...
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