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Article

Role of RAD52 Epistasis Group Genes in Homologous Recombination and Double-Strand Break Repair

1 Dec 2002

Abstract excerpt

The process of homologous recombination is a major DNA repair pathway that operates on DNA double-strand breaks, and possibly other kinds of DNA lesions, to promote error-free repair. Central to the process of homologous recombination are the RAD52 group genes (RAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2), most of which were identified by their requirement for the repair of...

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PMID: 12456786
DOI: 10.1128/mmbr.66.4.630-670.2002

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