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Article

Rad52 and Rad59 exhibit both overlapping and distinct functions.

DNA repair - 4 Jan 2007

Feng Qi, Düring Louis, de Mayolo Adriana Antúnez, Lettier Gaëlle, Lisby Michael, Erdeniz Naz, Mortensen Uffe H, Rothstein Rodney

Abstract excerpt

Homologous recombination is an important pathway for the repair of DNA double-strand breaks (DSBs). In the yeast Saccharomyces cerevisiae, Rad52 is a central recombination protein, whereas its paralogue, Rad59, plays a more subtle role in homologous recombination. Both proteins can mediate annealing of complementary single-stranded DNA in vitro, but only Rad52 interacts with replication protein A and the Rad51...

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Share to DNA Breaks, Double-Stranded
Share to DNA, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Replication

Share to DNA, Single-Stranded

Share to Genetic Complementation Test

Share to Rad51 Recombinase

Share to Rad52 DNA Repair and Recombination Protein

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Source

Identifiers

PMID: 16987715
DOI: 10.1016/j.dnarep.2006.08.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Rad52 and Rad59 exhibit both overlapping and distinct functions.PMID 16987715Read ↗

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