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Article

Vital roles of the second DNA-binding site of Rad52 protein in yeast homologous recombination.

The Journal of biological chemistry - 20 May 2011

Arai Naoto, Kagawa Wataru, Saito Kengo, Shingu Yoshinori, Mikawa Tsutomu, Kurumizaka Hitoshi, Shibata Takehiko

Abstract excerpt

RecA/Rad51 proteins are essential in homologous DNA recombination and catalyze the ATP-dependent formation of D-loops from a single-stranded DNA and an internal homologous sequence in a double-stranded DNA. RecA and Rad51 require a "recombination mediator" to overcome the interference imposed by the prior binding of single-stranded binding protein/replication protein A to the single-stranded DNA. Rad52 is the...

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Share to DNA, Fungal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Rad51 Recombinase

Share to Rad52 DNA Repair and Recombination Protein

Share to Recombination, Genetic

Share to Saccharomyces cerevisiae

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Share to Sequence Homology, Amino Acid

Source

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Identifiers

PMID: 21454474
DOI: 10.1074/jbc.M110.216739
PMCID: PMC3093836

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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