Article
Interaction of the TFIIB zinc ribbon with RNA polymerase II.
Biochemical Society transactions - 1 Aug 2008
Elsby Laura M, Roberts Stefan G E
Abstract excerpt
Transcription by RNA polymerase II requires the assembly of the general transcription factors at the promoter to form a pre-initiation complex. The general transcription factor TF (transcription factor) IIB plays a central role in the assembly of the pre-initiation complex, providing a bridge between promoter-bound TFIID and RNA polymerase II/TFIIF. We have characterized a series of TFIIB mutants in their ability...
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