Article
A common site on TBP for transcription by RNA polymerases II and III.
The EMBO journal - 1 Oct 2003
Schröder Oliver, Bryant Gene O, Geiduschek E Peter, Berk Arnold J, Kassavetis George A
Abstract excerpt
The TATA-binding protein (TBP) is involved in all nuclear transcription. We show that a common site on TBP is used for transcription initiation complex formation by RNA polymerases (pols) II and III. TBP, the transcription factor IIB (TFIIB)-related factor Brf1 and the pol III-specific factor Bdp1 constitute TFIIIB. A photochemical cross-linking approach was used to survey a collection of human TBP surface...
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