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Article

Position of the general transcription factor TFIIF within the RNA polymerase II transcription preinitiation complex.

The EMBO journal - 17 Feb 2010

Eichner Jesse, Chen Hung-Ta, Warfield Linda, Hahn Steven

Abstract excerpt

The RNA polymerase (pol) II general transcription factor TFIIF functions at several steps in transcription initiation including preinitiation complex (PIC) formation and start site selection. We find that two structured TFIIF domains bind Pol II at separate locations far from the active site with the TFIIF dimerization domain on the Pol II lobe and the winged helix domain of the TFIIF small subunit Tfg2 above the...

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Identifiers

PMID: 20033062
DOI: 10.1038/emboj.2009.386
PMCID: PMC2829161

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Source receipt: pubmed, retrieved 7 Sept 2026.

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