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Article

A nonconserved surface of the TFIIB zinc ribbon domain plays a direct role in RNA polymerase II recruitment.

Molecular and cellular biology - 1 Apr 2004

Tubon Thomas C, Tansey William P, Herr Winship

Abstract excerpt

The general transcription factor TFIIB is a highly conserved and essential component of the eukaryotic RNA polymerase II (pol II) transcription initiation machinery. It consists of a single polypeptide with two conserved structural domains: an amino-terminal zinc ribbon structure (TFIIB(ZR)) and a carboxy-terminal core (TFIIB(CORE)). We have analyzed the role of the amino-terminal region of human TFIIB in...

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Identifiers

PMID: 15024075
DOI: 10.1128/MCB.24.7.2863-2874.2004
PMCID: PMC371104

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Source receipt: pubmed, retrieved 7 Sept 2026.

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