Article
TAF1B is a TFIIB-like component of the basal transcription machinery for RNA polymerase I.
Science (New York, N.Y.) - 16 Sept 2011
Naidu Srivatsava, Friedrich J Karsten, Russell Jackie, Zomerdijk Joost C B M
Abstract excerpt
Transcription by eukaryotic RNA polymerases (Pols) II and III and archaeal Pol requires structurally related general transcription factors TFIIB, Brf1, and TFB, respectively, which are essential for polymerase recruitment and initiation events. A TFIIB-like protein was not evident in the Pol I basal transcription machinery. We report that TAF1B, a subunit of human Pol I basal transcription factor SL1, is...
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