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Article

CTLA-4 and multiple sclerosis: the A49G single nucleotide polymorphism shows no association with multiple sclerosis in a Southern Australian population.

Journal of neuroimmunology - 30 May 2008

Wray Bradley N, Stankovich Jim, Whittock Lucy, Dwyer Terence, Ponsonby Anne-Louise, van der Mei Ingrid A F, Taylor Bruce, Dickinson Joanne, Foote Simon, McMorran Brendan J

Abstract excerpt

Multiple sclerosis (MS) is a chronic autoimmune disorder that causes inflammatory demyelination and axonal damage in the central nervous system (CNS). We have investigated whether the A49G single nucleotide polymorphism (SNP) genotype of the CTLA-4 gene influenced the development of MS in Southern Australians as well as the interaction of this SNP with the DRB1*15 haplotype. There were no significant (P<0.05)...

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Source

Identifiers

PMID: 18378005
DOI: 10.1016/j.jneuroim.2008.02.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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