Article
CTLA-4 +49 A/G gene polymorphism in Croatian and Slovenian multiple sclerosis patients.
International journal of immunogenetics - 1 Oct 2011
Cizmarević N Starčević, Gašparović I, Peterlin B, Sepčić J, Rudolf G, Kapović M, Lavtar P, Ristić S
Abstract excerpt
Polymorphisms in the CTLA-4 gene are known to be important in several autoimmune diseases, including multiple sclerosis (MS). Previous studies on the impact of CTLA-4 +49 A/G gene polymorphism have given contradictory results. We investigated the possible influence of this polymorphism on MS susceptibility and disease behaviour in Croatian and Slovenian populations. Genotyping was performed in 367 patients with...
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