Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The CTLA-4 gene is associated with multiple sclerosis.

Journal of neuroimmunology - 1 Jun 1999

Ligers A, Xu C, Saarinen S, Hillert J, Olerup O

Abstract excerpt

We have investigated whether three intragenic polymorphisms of the CTLA-4 gene, a C/T base exchange in the promoter (p.-318), an A/G substitution in exon 1 (p.49) and a dinucleotide repeat polymorphism in exon 4 (p.642), were associated with genetic susceptibility to multiple sclerosis (MS). We o...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abatacept
Share to Antigens, Differentiation
Share to Chromosomes, Human, Pair 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CTLA-4 Antigen

Share to DNA, Satellite

Share to Immunoconjugates

Share to Immunosuppressive Agents

Share to T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 10408973
DOI: 10.1016/s0165-5728(99)00072-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10408973-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The CTLA-4 gene is associated with multiple sclerosis.PMID 10408973Read ↗

CTLA4 is associated with susceptibility to multiple sclerosis.Semantic proximity Read ↗

CTLA4 exon 1 dimorphism is associated with primary progressive multiple sclerosis.Semantic proximity Read ↗

CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms.Semantic proximity Read ↗

No evidence for association of CTLA-4 gene polymorphisms with the risk of developing multiple sclerosis: a meta-analysis.Semantic proximity Read ↗

Progression of multiple sclerosis is associated with exon 1 CTLA-4 gene polymorphism.Semantic proximity Read ↗

CTLA4 promoter and exon 1 dimorphisms in multiple sclerosis.Semantic proximity Read ↗

CTLA4 dimorphisms and the multiple sclerosis phenotype.Semantic proximity Read ↗

Association of common T cell activation gene polymorphisms with multiple sclerosis in Australian patients.Semantic proximity Read ↗

Genomic regulation of CTLA4 and multiple sclerosis.Semantic proximity Read ↗

CTLA-4 gene and the susceptibility of multiple sclerosis: an updated meta-analysis study including 12,916 cases and 15,455 controls.Semantic proximity Read ↗

The CTLA4 +49 A/G*G-CT60*G haplotype is associated with susceptibility to multiple sclerosis in Flanders.Semantic proximity Read ↗

CTLA-4 +49 A/G gene polymorphism in Croatian and Slovenian multiple sclerosis patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.