Article
Association of common T cell activation gene polymorphisms with multiple sclerosis in Australian patients.
Journal of neuroimmunology - 1 Mar 2004
Teutsch Suzy M, Booth David R, Bennetts Bruce H, Heard Robert N S, Stewart Graeme J
Abstract excerpt
Susceptibility to multiple sclerosis (MS) may be influenced by the interaction of several genes within a biological pathway. T cell activation and costimulation may be potentially important in MS pathogenesis. We have therefore investigated associations between MS and polymorphisms in the CD152 (CTLA-4), CD28, CD80 and CD86 genes in Australian patients. We found no significant MS association with CTLA-4 exon 1...
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