Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CTLA-4 +49 A/G and -318 C/T polymorphisms and susceptibility to multiple sclerosis: a meta-analysis.

Immunological investigations - 1 Jan 2013

Gyu Song Gwan, Ho Lee Young

Abstract excerpt

OBJECTIVE: The aim of this study was to explore whether cytotoxic T lymphocyte antigen-4 (CTLA-4) +49 A/G, and -318 C/T polymorphisms confer susceptibility to multiple sclerosis (MS). METHODS: A meta-analysis of the associations between the CTLA-4 +49 A/G and -318 C/T polymorphisms and MS. RESULTS: A total of 23 separate comparisons from 19 studies of the CTLA-4 +49 A/G polymorphism and 10 comparisons (8 studies)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CTLA-4 Antigen
Share to Ethnicity
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multiple Sclerosis

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 23802171
DOI: 10.3109/08820139.2013.803114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CTLA-4 +49 A/G and -318 C/T polymorphisms and susceptibility to multiple sclerosis: a meta-analysis.PMID 23802171Read ↗

CTLA-4 gene and the susceptibility of multiple sclerosis: an updated meta-analysis study including 12,916 cases and 15,455 controls.Semantic proximity Read ↗

CTLA-4 gene polymorphisms (-318C/T, +49A/G, +6230A/G) in Iranian patients with multiple sclerosis.Semantic proximity Read ↗

No evidence for association of CTLA-4 gene polymorphisms with the risk of developing multiple sclerosis: a meta-analysis.Semantic proximity Read ↗

Association between the CTLA-4 +49 A/G polymorphism and susceptibility to rheumatoid arthritis: a meta-analysis.Semantic proximity Read ↗

Cytotoxic T-lymphocyte-associated protein 4 gene polymorphism is related to rheumatoid arthritis in Egyptian population.Semantic proximity Read ↗

CTLA-4 +49 A/G gene polymorphism in Croatian and Slovenian multiple sclerosis patients.Semantic proximity Read ↗

Cytotoxic T lymphocyte associated antigen-4 exon 1 A/G polymorphism in Iranian patients with multiple sclerosis.Semantic proximity Read ↗

The effect of CTLA-4 A49G polymorphism on rheumatoid arthritis risk: a meta-analysis.Semantic proximity Read ↗

The CTLA-4 gene is associated with multiple sclerosis.Semantic proximity Read ↗

Association between 318C/T polymorphism of the CTLA-4 gene and systemic lupus erythematosus in Iranian patients.Semantic proximity Read ↗

Meta-analysis of the association of CTLA-4 exon-1 +49A/G polymorphism with rheumatoid arthritis.Semantic proximity Read ↗

Lack of association between CTLA-4 +49A/G and -318C/T polymorphisms and Behçet's disease risk: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.