Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple sclerosis susceptibility-associated SNPs do not influence disease severity measures in a cohort of Australian MS patients.

PloS one - 2 Apr 2010

Jensen Cathy J, Stankovich Jim, Van der Walt Anneke, Bahlo Melanie, Taylor Bruce V, van der Mei Ingrid A F, Foote Simon J, Kilpatrick Trevor J, Johnson Laura J, Wilkins Ella, Field Judith, Danoy Patrick, Brown Matthew A, Rubio Justin P, Butzkueven Helmut

Abstract excerpt

Recent association studies in multiple sclerosis (MS) have identified and replicated several single nucleotide polymorphism (SNP) susceptibility loci including CLEC16A, IL2RA, IL7R, RPL5, CD58, CD40 and chromosome 12q13-14 in addition to the well established allele HLA-DR15. There is potential that these genetic susceptibility factors could also modulate MS disease severity, as demonstrated previously for the MS...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Atrophy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Australia

Share to Cognition

Share to Disability Evaluation

Share to Multiple Sclerosis

Share to Severity of Illness Index

Source

Open in PubMed Open full text

Identifiers

PMID: 20368992
DOI: 10.1371/journal.pone.0010003
PMCID: PMC2848851

Genes

RPL5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple sclerosis susceptibility-associated SNPs do not influence disease severity measures in a cohort of Australian MS patients.PMID 20368992Read ↗

Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studiesSemantic proximity Read ↗

Not all roads lead to the immune system: The Genetic Basis of Multiple Sclerosis Severity Implicates Central Nervous System and Mitochondrial InvolvementSemantic proximity Read ↗

Heterogeneity at the HLA-DRB1 allelic variation locus does not influence multiple sclerosis disease severity, brain atrophy or cognition.Semantic proximity Read ↗

Unlocking Multiple Sclerosis GeneticsSemantic proximity Read ↗

Not all roads lead to the immune system: the genetic basis of multiple sclerosis severitySemantic proximity Read ↗

Replication of KIAA0350, IL2RA, RPL5 and CD58 as multiple sclerosis susceptibility genes in Australians.Semantic proximity Read ↗

Genome-wide association study of severity in multiple sclerosis.Semantic proximity Read ↗

Multiple sclerosis susceptibility loci do not alter clinical and MRI outcomes in clinically isolated syndrome.Semantic proximity Read ↗

No evidence for an effect of DNA methylation on multiple sclerosis severity at HLA-DRB1*15 or HLA-DRB5.Semantic proximity Read ↗

Role of genetic susceptibility variants in predicting clinical course in multiple sclerosis: a cohort study.Semantic proximity Read ↗

Immune-Related Gene Variants as Modifiers of Multiple Sclerosis Severity.Semantic proximity Read ↗

No influence on disease progression of non-HLA susceptibility genes in MS.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.