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Article

The influence of non-HLA gene polymorphisms and interactions on disease risk in a Western Australian multiple sclerosis cohort.

Journal of neuroimmunology - 15 Aug 2013

Qiu Wei, Pham Kym, James Ian, Nolan David, Castley Allison, Christiansen Frank T, Czarniak Petra, Luo Yuebei, Wu Jingshan, Garlepp Michael, Wilton Steve, Carroll William M, Mastaglia Frank L, Kermode Allan G

Abstract excerpt

Non-Human Leukocyte Antigen (HLA) genes have concomitant, although modest, effects on multiple sclerosis (MS) susceptibility; however findings have varied in different populations. Here we present the results of an association study of 16 single nucleotide polymorphisms (SNPs) in 10 non-HLA genes (IL7R, IL2RA, CLEC-16A, TYK2, CD58, IRF5, STAT3, CTLA-4, APOE, ICAM-1) in a Western Australian cohort of 350 MS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23726763
DOI: 10.1016/j.jneuroim.2013.04.022

Genes

TYK2
APOE
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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