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Article

Polymorphisms in toll-like receptor genes and susceptibility to pulmonary aspergillosis.

The Journal of infectious diseases - 15 Feb 2008

Carvalho A, Pasqualotto A C, Pitzurra L, Romani L, Denning D W, Rodrigues F

Abstract excerpt

Toll-like receptors (TLRs) are important components of innate immunity. We investigated the association between polymorphisms in the TLR2, TLR4, and TLR9 genes and susceptibility to noninvasive forms of pulmonary aspergillosis. A significant association was observed between allele G on Asp299Gly (TLR4) and chronic cavitary pulmonary aspergillosis (odds ratio [OR], 3.46; P =.003). Susceptibility to allergic...

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Source

Identifiers

PMID: 18275280
DOI: 10.1086/526500

Genes

TLR4
TLR9
TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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