Article
Polymorphisms in Toll-like receptor genes and susceptibility to infections in allogeneic stem cell transplantation.
Experimental hematology - 1 Sept 2009
Carvalho Agostinho, Cunha Cristina, Carotti Alessandra, Aloisi Teresa, Guarrera Ornella, Di Ianni Mauro, Falzetti Franca, Bistoni Francesco, Aversa Franco, Pitzurra Lucia, Rodrigues Fernando, Romani Luigina
Abstract excerpt
OBJECTIVE: Discovery of genetic variations in the genes encoding for Toll-like receptors (TLRs) has highlighted a potential link between genomic variation of the host and susceptibility to infections. MATERIALS AND METHODS: We investigated the association between polymorphisms in the TLR2, TLR4, and TLR9 genes in recipients of allogeneic hematopoietic stem cell transplant and susceptibility to infections caused...
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