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Article

TLR4 polymorphisms and disease susceptibility.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Mar 2012

Noreen Mamoona, Shah Muhammad Ali A, Mall Sheeba Murad, Choudhary Shazia, Hussain Tahir, Ahmed Iltaf, Jalil Syed Fazal, Raza Muhammad Imran

Abstract excerpt

Toll-like receptors (TLRs) play a central role in the regulation of the host immune system. Each TLR recognizes specific pathogen-associated molecular patterns (PAMPs). TLR4 is one of the well characterized pathogen recognition receptors (PRRs) that recognizes the lipopolysaccharide (LPS) of Gram-negative bacteria, some conserved structures from fungal to mycobacterial pathogens and some endogenous ligands. A...

Topics

Animals
Communicable Diseases
Genetic Predisposition to Disease
Humans
Lipopolysaccharides
Polymorphism, Genetic
Signal Transduction
Toll-Like Receptor 4

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22277994
DOI: 10.1007/s00011-011-0427-1

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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