Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variations in toll-like receptor pathway genes influence asthma and atopy.

Allergy - 1 Mar 2011

Tesse R, Pandey R C, Kabesch M

Abstract excerpt

Innate immunity is a pivotal defence system of higher organisms. Based on a limited number of receptors, it is capable of recognizing pathogens and to initiate immune responses. Major components of these innate immunity pathogen recognition receptors are the toll-like receptors (TLRs), a family of 11 in humans. They are all membrane bound and through dimerization and complex downstream signaling, TLRs elicit a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma
Share to Environment
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hypersensitivity

Share to Immunity, Innate

Share to Lipopolysaccharide Receptors

Share to Signal Transduction

Share to Toll-Like Receptors

Source

Identifiers

PMID: 21039600
DOI: 10.1111/j.1398-9995.2010.02489.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variations in toll-like receptor pathway genes influence asthma and atopy.PMID 21039600Read ↗

Toll-like receptor polymorphisms, inflammatory and infectious diseases, allergies, and cancer.Semantic proximity Read ↗

The Effect of Toll-Like Receptors and Toll-Like Receptor Genetics in Human DiseaseSemantic proximity Read ↗

TLR-related pathway analysis: novel gene-gene interactions in the development of asthma and atopy.Semantic proximity Read ↗

Toll-like receptor heterodimer variants protect from childhood asthma.Semantic proximity Read ↗

Allergy Takes its Toll: The Role of Toll-like Receptors in Allergy PathogenesisSemantic proximity Read ↗

The role of Toll-like receptors and related receptors of the innate immune system in asthmaSemantic proximity Read ↗

Association of TLR1, TLR2, TLR4, TLR6, and TIRAP polymorphisms with disease susceptibility.Semantic proximity Read ↗

TLR4 polymorphisms and disease susceptibility.Semantic proximity Read ↗

An association study of asthma and total serum immunoglobin E levels for Toll‐like receptor polymorphisms in a Japanese populationSemantic proximity Read ↗

Toll-like receptor polymorphisms and susceptibility to human disease.Semantic proximity Read ↗

Genetic variation in Toll-like receptor signalling and the risk of inflammatory and immune diseases.Semantic proximity Read ↗

Gene–environment interactions in asthma and allergy: the end of the beginning?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.