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Article

Polymorphisms in Innate and Adaptive Immune Genes in Subjects with Allergic Bronchopulmonary Aspergillosis Complicating Asthma.

Mycopathologia - 26 Feb 2024

Kanaujia Rimjhim, Arora Amit, Chakrabarti Arunaloke, Rudramurthy Shivaprakash M, Agarwal Ritesh

Abstract excerpt

Innate and adaptive immunity play a crucial role in allergic bronchopulmonary aspergillosis (ABPA) pathogenesis. We performed next-generation sequencing using the Illumina TruSight One panel (4,811 human disease-associated genes, at least 20 × coverage) and selected 22 known immune genes (toll-like receptors (TLRs), C-type lectin, interleukin-4 receptor, and others). We included ABPA (n = 18), asthma without ABPA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38407762
DOI: 10.1007/s11046-024-00834-5

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