Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variants in toll-like receptors 2 and 9 influence susceptibility to pulmonary tuberculosis in Caucasians, African-Americans, and West Africans.

Human genetics - 1 Jan 2010

Velez Digna Rosa, Wejse Christian, Stryjewski Martin E, Abbate Eduardo, Hulme William F, Myers Jamie L, Estevan Rosa, Patillo Sara G, Olesen Rikke, Tacconelli Alessandra, Sirugo Giorgio, Gilbert John R, Hamilton Carol D, Scott William K

Abstract excerpt

Tuberculosis (TB) is a global public health problem and a source of preventable deaths each year, with 8.8 million new cases of TB and 1.6 million deaths worldwide in 2005. Approximately, 10% of infected individuals develop pulmonary or extrapulmonary TB, suggesting that host defense factors influence development of active disease. Toll-like receptor' (TLR) polymorphisms have been associated with regulation of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Black People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Toll-Like Receptor 2

Share to Toll-Like Receptor 9

Share to Tuberculosis, Pulmonary

Share to United States

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 19771452
DOI: 10.1007/s00439-009-0741-7
PMCID: PMC2902366

Genes

TLR2
TLR9
TLR1
TLR4
TLR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variants in toll-like receptors 2 and 9 influence susceptibility to pulmonary tuberculosis in Caucasians, African-Americans, and West Africans.PMID 19771452Read ↗

Association of Toll-like Receptors 1, 2, 4, 6, 8, 9 and 10 Genes Polymorphisms and Susceptibility to Pulmonary Tuberculosis in Sudanese PatientsSemantic proximity Read ↗

Association between toll-like receptors 9 (TLR9) gene polymorphism and risk of pulmonary tuberculosis: meta-analysis.Semantic proximity Read ↗

Association of polymorphisms in Toll-like receptors 4 and 9 with risk of pulmonary tuberculosis: a meta-analysis.Semantic proximity Read ↗

Single Nucleotide Polymorphisms in TLR4 Affect Susceptibility to Tuberculosis in Mexican Population from the State of Veracruz.Semantic proximity Read ↗

TLR1, 2, 4, 6 and 9 Variants Associated with Tuberculosis Susceptibility: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Influence of Toll-like receptor gene polymorphisms to tuberculosis susceptibility in humans.Semantic proximity Read ↗

Association of Toll –like Receptors 1, 2, 4, 6 ,8, 9 and 10 Genes Polymorphisms and Susceptibility to Tuberculosis in Sudanese PatientsSemantic proximity Read ↗

Toll-like receptor -1, -2, and -6 polymorphisms and pulmonary tuberculosis susceptibility: a systematic review and meta-analysis.Semantic proximity Read ↗

Variants in toll-like receptor 9 gene influence susceptibility to tuberculosis in a Mexican population.Semantic proximity Read ↗

Human Toll-like receptor 2 genetic polymorphisms with tuberculosis susceptibility: A systematic review and meta-analysis.Semantic proximity Read ↗

Association of TLR polymorphisms with development of tuberculosis in Indonesian females.Semantic proximity Read ↗

The Role of Toll-like Receptor 2 Polymorphisms in Susceptibility to and Severity of Tuberculosis: A Systematic Review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.