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Article

COMT val158met genotype affects recruitment of neural mechanisms supporting fluid intelligence.

Cerebral cortex (New York, N.Y. : 1991) - 1 Sept 2008

Bishop Sonia J, Fossella John, Croucher Camilla J, Duncan John

Abstract excerpt

Fluid intelligence (g(f)) influences performance across many cognitive domains. It is affected by both genetic and environmental factors. Tasks tapping g(f) activate a network of brain regions including the lateral prefrontal cortex (LPFC), the presupplementary motor area/anterior cingulate cortex (pre-SMA/ACC), and the intraparietal sulcus (IPS). In line with the "intermediate phenotype" approach, we assessed...

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Identifiers

PMID: 18252743
DOI: 10.1093/cercor/bhm240
PMCID: PMC2517101

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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