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Article

Genes, cognition and brain through a COMT lens.

Neuroscience - 24 Nov 2009

Dickinson D, Elvevåg B

Abstract excerpt

Various genes are known to modulate the delicate balance of dopamine in prefrontal cortex and influence cortical information processing. Catechol-O-methyltransferase (COMT) on chromosome 22q11 is the most widely studied of these genes. Val158Met, a common, functional variant in the coding sequence that increases or decreases the enzymatic activity of the gene has been shown to impact the efficiency of...

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Identifiers

PMID: 19446012
DOI: 10.1016/j.neuroscience.2009.05.014
PMCID: PMC2760675

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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