Article
CYP2F1 genetic polymorphism: identification of interethnic variations.
Xenobiotica; the fate of foreign compounds in biological systems - 1 Dec 2007
Tournel G, Cauffiez C, Leclerc J, Billaut-Laden I, Allorge D, Chevalier D, Migot-Nabias F, Kenani A, Broly F, Lo-Guidice J -M
Abstract excerpt
Since human cytochrome P450 2F1 (CYP2F1) is predominantly expressed in lung tissue and is involved in the metabolism of various pneumotoxicants with potential carcinogenic effects, variations in the nucleotidic sequence of its gene may contribute to interindividual and interethnic differences in the susceptibility to lung tumorigenesis. The aim of the current study was to compare the frequency of a previously...
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