Article
Polymorphism of the CYP1A1*2A gene and susceptibility to lung cancer in a Brazilian population.
Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia - 1 Aug 2009
Honma Helen Naemi, De Capitani Eduardo Mello, Barbeiro Aristóteles de Souza, Costa Daniel Botelho, Morcillo André, Zambon Lair
Abstract excerpt
OBJECTIVE: To estimate and compare the frequency of CYP1A1*2A gene polymorphisms in a Brazilian population and determine the possible contribution of these genetic variations to lung cancer risk. METHODS: The study population included 200 patients with lung cancer, and the control group consisted of 264 blood donors. Genomic DNA was obtained from peripheral blood samples. The PCR-RFLP method was used for analysis...
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