Article
Genetic polymorphisms of CYP1A1, GSTM1 and P53 genes in a unique Siberian population of Tundra Nentsi and its pharmacogenetic importance.
International journal of circumpolar health - 1 Apr 2001
Duzhak T G, Osipova L P, Posukh O L, Chasovnikova O B, Ostashevskii V I, Lyakhovich V V
Abstract excerpt
Complete data on the polymorphisms of CYP1A1, GSTM1 and p53 genes in Tundra Nentsi population, with known genealogical history are essential for the analysis of the "cancer susceptibility gene markers" distribution among different Oriental populations. The cytochrome P4501A subfamily is known to be responsible for the metabolic activation of aromatic compounds occurring in the products of gas mixture combustion,...
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