Article
Association of CYP1B1 Leu432Val polymorphism and lung cancer risk: an updated meta-analysis.
Lung - 1 Oct 2014
Lao Xianjun, Qin Xue, Peng Qiliu, Chen Zhiping, Lu Yu, Liu Yanqiong, Li Shan
Abstract excerpt
BACKGROUND: Cytochrome P4501B1 (CYP1B1) a phase I enzyme, is involved in the activation of a broad spectrum of procarcinogens. Impacts on the catalytic activity of the CYP1B1 enzyme, as well as an association of the Leu432Val polymorphism with the risk of lung cancer, have been described; however, the results remain controversial. METHODS: We conducted a meta-analysis of all available studies to clarify the...
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