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Article

CYP1A1 and CYP1B1 polymorphisms and risk of lung cancer among never smokers: a population-based study.

Carcinogenesis - 1 Dec 2005

Wenzlaff A S, Cote M L, Bock C H, Land S J, Santer S K, Schwartz D R, Schwartz A G

Abstract excerpt

The cytochrome P450 (CYP) superfamily of enzymes catalyse one of the first steps in the metabolism of carcinogens such as polycyclic aromatic hydrocarbons, nitroaromatics and arylamines. Polymorphisms within the CYP1A1 gene have been shown to be associated with lung cancer risk, predominantly among Asian populations. Despite functional evidence of a possible role of CYP1B1 in lung cancer susceptibility, only a...

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Identifiers

PMID: 16051642
DOI: 10.1093/carcin/bgi191

Genes

NQO1
GSTM1
GSTP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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