Article
Cytochrome P4502E1 (CYP2E1) genetic polymorphisms in a Lebanese population: frequency distribution and association with morbid diseases.
Genetic testing and molecular biomarkers - 1 Jun 2010
Zgheib Nathalie Khoueiry, Mitri Zahi, Geryess Eddy, Noutsi Pakiza
Abstract excerpt
BACKGROUND: The drug-metabolizing enzyme CYP2E1 is of great interest in environmental medicine because of its involvement in the bioactivation of multiple procarcinogens. AIM: This study is aimed at determining the frequency of genetic polymorphisms of the three restriction fragment length polymorphisms: PstI and RsaI (CYP2E1*5B) and DraI (CYP2E1*6) in 216 cancer-free Lebanese individuals, as well as assessing...
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