Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CYP1A1 m1 and m2 polymorphisms: genetic susceptibility to lung cancer.

Revista portuguesa de pneumologia - 1 Jan 2000

Mota Paula, Moura David Silva, Vale Maria Graça, Coimbra Henriqueta, Carvalho Lina, Regateiro Fernando

Abstract excerpt

Lung cancer is considered an environment-related disease that develops as a consequence of exposure to mutagenic agents, namely those present in tobacco. The CYP1A1 gene codifies the phase I enzyme aryl hydrocarbon hydroxilase (AHH) belonging to the cytochrome P450 system that plays a major role in the bio-activation of tobacco procarcinogenes. Two CYP1A1 polymorphisms, m1 (T6235C transition) and m2 (A4889G...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytochrome P-450 CYP1A1
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lung Neoplasms

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 20054510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CYP1A1 m1 and m2 polymorphisms: genetic susceptibility to lung cancer.PMID 20054510Read ↗

CYP1A1 gene polymorphisms and smoking status as modifier factors for lung cancer risk.Semantic proximity Read ↗

Genetic polymorphisms of CYP1A1 and GSTM1 and lung cancer risk.Semantic proximity Read ↗

Genetic polymorphisms of phase I and phase II metabolic enzymes as modulators of lung cancer susceptibility.Semantic proximity Read ↗

Genetic susceptibility to lung cancer with special emphasis on CYP1A1 and GSTM1: a study on host factors in relation to age at onset, gender and histological cancer types.Semantic proximity Read ↗

Polymorphisms in the human CYP1A1 gene as susceptibility factors for lung cancer: exon-7 mutation (4889 A to G), and a T to C mutation in the 3'-flanking region.Semantic proximity Read ↗

Polymorphism of the CYP1A1*2A gene and susceptibility to lung cancer in a Brazilian population.Semantic proximity Read ↗

CYP1A1 *2B and *4 polymorphisms are associated with lung cancer susceptibility in Mexican patients.Semantic proximity Read ↗

Glutathione S-transferase mu polymorphism and susceptibility to lung cancer in the Portuguese population.Semantic proximity Read ↗

Genetic polymorphisms of CYP1A1, GSTM1 and GSTT1 genes and lung cancer risk.Semantic proximity Read ↗

Genetic polymorphism of xenobiotic metabolising enzymes in Slovenian lung cancer patients.Semantic proximity Read ↗

Glutathione S-transferase M1 and P1 metabolic polymorphism and lung cancer predisposition.Semantic proximity Read ↗

CYP1A1 gene polymorphisms increase lung cancer risk in a high-incidence region of Spain: a case control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.