Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chemoconvulsant-induced seizure susceptibility: toward a common genetic basis?

Epilepsia - 1 Jan 2007

Chaix Yohan, Ferraro Thomas N, Lapouble Eve, Martin Benoît

Abstract excerpt

Despite the efforts employed, understanding the genetic architecture underlying epilepsy remains difficult. To reach this aim, convulsive epilepsies are classically modeled in mice, where genetic studies are less constricting than in humans. Pharmacogenetic approaches are one major source of investigation where kainic acid, pentylenetetrazol, and the ss-carboline family represent compounds that are used...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes
Share to Kainic Acid
Share to Mice, Inbred DBA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred Strains

Share to Pentylenetetrazole

Share to Potassium Channels

Share to Quantitative Trait Loci

Share to Seizures

Source

Identifiers

PMID: 17910581
DOI: 10.1111/j.1528-1167.2007.01289.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chemoconvulsant-induced seizure susceptibility: toward a common genetic basis?PMID 17910581Read ↗

Mapping quantitative trait loci for seizure response to a GABAA receptor inverse agonist in mice.Semantic proximity Read ↗

Mapping loci for pentylenetetrazol-induced seizure susceptibility in mice.Semantic proximity Read ↗

A locus on mouse Ch10 influences susceptibility to limbic seizure severity: fine mapping and in silico candidate gene analysis.Semantic proximity Read ↗

Mapping murine loci for seizure response to kainic acid.Semantic proximity Read ↗

Phenotyping mouse chromosome substitution strains reveal multiple QTLs for febrile seizure susceptibility.Semantic proximity Read ↗

Collaborative Cross mice reveal extreme epilepsy phenotypes and genetic loci for seizure susceptibility.Semantic proximity Read ↗

Genotyping microsatellite polymorphisms by agarose gel electrophoresis with ethidium bromide staining: application to quantitative trait loci analysis of seizure susceptibility in mice.Semantic proximity Read ↗

Fine mapping of a seizure susceptibility locus on mouse Chromosome 1: nomination of Kcnj10 as a causative gene.Semantic proximity Read ↗

Quantitative genetic study of maximal electroshock seizure threshold in mice: evidence for a major seizure susceptibility locus on distal chromosome 1.Semantic proximity Read ↗

Multidimensional Genetic Analysis of Repeated Seizures in the Hybrid Mouse Diversity Panel Reveals a Novel Epileptogenesis Susceptibility Locus.Semantic proximity Read ↗

A major effect QTL determined by multiple genes in epileptic EL mice.Semantic proximity Read ↗

Cocaine-induced seizure thresholds: quantitative trait loci detection and mapping in two populations derived from the C57BL/6 and DBA/2 mouse strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.