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Article

Mapping murine loci for seizure response to kainic acid.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 1997

Ferraro T N, Golden G T, Smith G G, Schork N J, St Jean P, Ballas C, Choi H, Berrettini W H

Abstract excerpt

Mature DBA/2J (D2) mice are very sensitive to seizures induced by various chemical and physical stimuli, whereas C57BL/6J (B6) mice are relatively seizure resistant. We have conducted a genome-wide search for quantitative trait loci (QTLs) influencing the differential sensitivity of these strains to kainic acid (KA)-induced seizures by studying an F2 intercross population. Parental, F1, and F2 mice (8-10 weeks of...

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PMID: 9069121
DOI: 10.1007/s003359900389

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Source receipt: pubmed, retrieved 7 Sept 2026.

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