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Article

Multidimensional Genetic Analysis of Repeated Seizures in the Hybrid Mouse Diversity Panel Reveals a Novel Epileptogenesis Susceptibility Locus.

G3 (Bethesda, Md.) - 7 Aug 2017

Ferland Russell J, Smith Jason, Papandrea Dominick, Gracias Jessica, Hains Leah, Kadiyala Sridhar B, O'Brien Brittany, Kang Eun Yong, Beyer Barbara S, Herron Bruce J

Abstract excerpt

Epilepsy has many causes and comorbidities affecting as many as 4% of people in their lifetime. Both idiopathic and symptomatic epilepsies are highly heritable, but genetic factors are difficult to characterize among humans due to complex disease etiologies. Rodent genetic studies have been critical to the discovery of seizure susceptibility loci, including Kcnj10 mutations identified in both mouse and human...

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Share to Chromosomes, Mammalian
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28620084
DOI: 10.1534/g3.117.042234
PMCID: PMC5555461

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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